In our reality, Jessica Drew became deathly ill due to exposure to the radioactive uranium as a child. To save her life, she was injected with an experimental serum composed of irradiated spider's blood and placed in a genetic accelerator where she remained in partial cryogenic suspension for decades, aging at a reduced rate. Released from the tube after her radiation poisoning had been cured, the treatment had mutated her cellular structure, giving her vast strength, an immunity to all toxic substances and radiation, and the capability to generate bioelectric energy which she could discharge as sparks. She was found by the subversive organization Hydra as she was fleeing from a mob after accidentally killing her lover with accidentally discharged bioelectricity. Recognizing the young woman's unique abilities, Hydra put her through rigorous espionage and martial arts training and brainwashed her to believe she was a highly evolved spider rather than a real woman. Her first mission was to assassinate S.H.I.E.L.D. Director Nick Fury. Upon learning Hydra was evil, Jessica betrayed the organization and fled, now calling herself the Spider-Woman.

007)		Zero Tolerance (On The Offensive) Appearances: 2 Spider-Woman was being held at a Maximum Security Prison until she was freed by Charles Xavier who recruited her to be one of his X-Men. Hellbent on the extermination of the human race, they attacked the New York Stock Exchange to destroy the world's economy, but they were stopped cold by the Exiles. Unlike the Jessica Drew of our world, this version was an African-American.
036)		Legacy (Role Reversal) Appearances: 20, 21, 22, 34 The Spider-Woman in the world run by Vi-Locks is really Mary Jane Watson.
039)		Iron Monarchy (Ready Room) Appearances: 25 The Spider-Woman in the world ruled by Iron Man is really Julia Carpenter.